DocumentClosedpublication
Onderstepoort Biological Products Limited publication
Onderstepoort Biological Products LimitedRef: https://www.obpvaccines.co.za/web/wp-content/uploads/2026/07/Immunization-schedule-CATTLE.pdf
Official source
Source domain: obpvaccines.co.za
Collected on 17 July 2026
Always confirm details on the official source before acting.
What this means
This document is an immunisation schedule and vaccine product catalogue section for cattle (and some other species). It provides recommended timing and dosing for essential and additional vaccines for cattle, including pre-breeding, pre-calving, and early-life vaccinations, and it also includes guidance for sustained booster programmes in adult cattle. It further lists specific vaccine compositions, species indications, dosages, presentations, and regulatory registration numbers, including storage instructions for frozen vaccines (dry ice/liquid nitrogen, not a household freezer).
Facts
Reference
https://www.obpvaccines.co.za/web/wp-content/uploads/2026/07/Immunization-schedule-CATTLE.pdf
Key Takeaways
- Cattle immunisation schedule: initial vaccination must follow farm management/breeding programmes; schedule can be changed to fit farm needs
- Pre-breeding (6–8 weeks before): Rift Valley Fever (inactivated or live) 2 ml (subcutaneously) or 1 ml (subcutaneously); Vibriosis 1st injection 2 ml (heifers) or 5 ml (bulls) subcutaneously
- Pre-breeding (3–4 weeks before): Vibriosis 2nd injection 2 ml (heifers) or 5 ml (bulls) subcutaneously
- Pre-calving (8 weeks before, heifers): Escherichia coli 1st injection 2 ml intramuscularly; 2–4 weeks before calving: Escherichia coli 2nd injection 2 ml intramuscularly
- Age 7–14 days: Paratyphoid (live or inactivated) 5 ml subcutaneously (live/inactivated) or 10 ml subcutaneously (inactivated for cows)
- Heartwater (endemic areas, <21 days of age): listed as an essential vaccine with timing but dosage not fully shown in the extracted text
- Frozen vaccine storage rule (applies to Heartwater, Anaplasmosis, Redwater): keep on dry ice or liquid nitrogen (< -70°C); household freezer (-18°C) not suitable; thawed vaccine is ineffective; thawed vaccine must not be refrozen; thawed vaccine usable up to 4 hours if kept on melting ice
- Adult cattle sustained programme: yearly or six-monthly booster injections can be used in an annual breeding programme (example given for April–June and other periods)
- Cattle
- Heifers
- Bulls
- Rift Valley Fever
- Vibriosis
- Escherichia coli
- Paratyphoid
- Heartwater
- Pasteurella multocida
- Mannheimia (Pasteurella) haemolytica
- Trueperella pyogenes
- Clostridium chauvoei
- Clostridium novyi A
- Clostridium septicum
- Clostridium perfringens (welchii) type B
- Salmonella gallinarum
- Ehrlichia ruminantium
- Anaplasma centrale
- Babesia bovis
- Babesia bigemina
- Bibersteinia trehalosi
- Botulism/Black Quarter